The Flow Cytometry Laboratory
Room 311D
Department of Pathology
The University of Texas
Health Science Center at San Antonio
San Antonio, Texas
78284-7750
Phone: (210) 567-4096
Fax: (210) 567-2367
The Flow Cytometry Laboratory provides complete immunophenotypic analysis by multi
parameter flow cytometry and detection of terminal deoxynucleotidase (TdT) by
immunofluorescence staining. The assays are of value in the diagnosis and surveillance of
Leukemia (acute and chronic), Lymphoma, and immunodeficiency and immune altered states.
Leukemia and lymphoma
Flow cytomoetry and TdT staining are useful in the diagnosis and classification of acute
leukemia, the diagnosis and classification of non-Hodgkin's lymphoma and the detection of
residual leukemia or lymphoma following therapy. Analysis by the Flow Cytometry Laboratory
includes morphologic evaluation by a pathologist with experience in hematopathology,
selection of a suitable panel of immunophenotypic markers, notification of results by
telephone within 24 hours of receipt of the specimen and mailed or faxed report including
an interpretation of the data.
Immunodeficiency states
Flow cytometry is used for the monitoring of Human Immunodeficiency Virus (HIV) infection,
diagnosis of congenital immunodeficiency states, and analysis of iatrogenic
immunodeficiency. The Flow Cytometry Laboratory performs a complete immunophenotypic
analysis following guidelines provided by the CDC. The report includes the perecentages
and absolute counts for T-cell subsets, B-cell and natural killer (NK) cells, as well as a
summary of any previous results.
Immune altered states
Flow cytometry is of value in detecting and monitoring immune altered states associated
with autoimmune diseases, exposure to toxic chemicals, and drug therapy.
Specimen Requirements: